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Western blot analysis of extracts of various cell lines, using BTNL2 antibody (A7120) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
BTNL2 Rabbit pAb
Catalog No：AB-A7120
Manufacturer：ABclonal
Synonyms：BTNL2;BTL-II;BTN7;HSBLMHC1;SS2
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | BTNL2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 246-455 of human BTNL2 (NP_062548.1). |
| Gene ID: | 56244 |
| Swiss prot: | Q9UIR0 |
| Molecular weight: | 19kDa/27kDa/28kDa/30kDa/43kDa/50kDa |
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