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Western blot analysis of extracts of various cell lines, using ACTL6B antibody (A7108) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 40s.
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Immunohistochemistry of paraffin-embedded human kidney using ACTL6B antibody (A7108) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human kidney cancer using ACTL6B antibody (A7108) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse jejunum using ACTL6B antibody (A7108) at dilution of 1:100 (40x lens).
ACTL6B Rabbit pAb
Catalog No：AB-A7108
Manufacturer：ABclonal
Synonyms：ACTL6B;ACTL6;BAF53B;arpNalpha
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | ACTL6B Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ACTL6B (NP_057272.1). |
| Gene ID: | 51412 |
| Swiss prot: | O94805 |
| Molecular weight: | 46kDa |
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