Western blot analysis of extracts of various cell lines, using STC2 antibody (A10397) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
STC2 Rabbit pAb
Catalog No:AB-A10397
Manufacturer:ABclonal
Synonyms:STC2;STC-2;STCRP
Applications:WB
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | STC2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-302 of human STC2 (NP_003705.1). |
Gene ID: | 8614 |
Swiss prot: | O76061 |
Molecular weight: | 33kDa |
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