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Western blot analysis of extracts of various cell lines, using AGR2 antibody (A7064) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
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Immunohistochemistry of paraffin-embedded Human lung cancer using AGR2 Rabbit pAb (A7064) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded Mouse lung using AGR2 Rabbit pAb (A7064) at dilution of 1:100 (40x lens).
AGR2 Rabbit pAb
Catalog No：AB-A7064
Manufacturer：ABclonal
Synonyms：AGR2;AG-2;AG2;GOB-4;HAG-2;HEL-S-116;HPC8;PDIA17;XAG-2
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | AGR2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-175 of human AGR2 (NP_006399.1). |
| Gene ID: | 10551 |
| Swiss prot: | O95994 |
| Molecular weight: | 19kDa |
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