Western blot analysis of extracts of mouse testis, using ERCC8 Antibody (A6884) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
ERCC8 Rabbit pAb
Catalog No:AB-A6884
Manufacturer:ABclonal
Synonyms:ERCC8;CKN1;CSA;UVSS2
Applications:WB
Reactivity:Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ERCC8 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human ERCC8 (NP_000073.1). |
Gene ID: | 1161 |
Swiss prot: | Q13216 |
Molecular weight: | 23kDa/44kDa |
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