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Western blot analysis of extracts of RD cells, using Fbx32/FBOX32 antibody (A6825) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
Fbx32/FBOX32 Rabbit pAb
Catalog No：AB-A6825
Manufacturer：ABclonal
Synonyms：FBXO32;Fbx32;MAFbx
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | Fbx32/FBOX32 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Immunogen: | A synthetic peptide of human Fbx32/FBOX32 |
| Gene ID: | 114907 |
| Swiss prot: | Q969P5 |
| Molecular weight: | 30kDa/41kDa |
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