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Western blot analysis of extracts of various cell lines, using TIN2/TIN2/TINF2 antibody (A6769) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
TIN2/TINF2 Rabbit pAb
Catalog No：AB-A6769
Manufacturer：ABclonal
Synonyms：TINF2;DKCA3;TIN2
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | TIN2/TINF2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 202-451 of human TIN2/TIN2/TINF2 (NP_001092744.1). |
| Gene ID: | 26277 |
| Swiss prot: | Q9BSI4 |
| Molecular weight: | 15kDa/39kDa/50kDa |
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