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Western blot analysis of extracts of various cell lines, using CD207 antibody (A6553) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
CD207 Rabbit pAb
Catalog No：AB-A6553
Manufacturer：ABclonal
Synonyms：CD207;CLEC4K
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | CD207 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 69-328 of human CD207 (NP_056532.4). |
| Gene ID: | 50489 |
| Swiss prot: | Q9UJ71 |
| Molecular weight: | 36kDa |
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