Western blot analysis of extracts of various cell lines, using IL18BP antibody (A6445) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
IL18BP Rabbit pAb
Catalog No:AB-A6445
Manufacturer:ABclonal
Synonyms:IL18BP;IL18BPa
Applications:WB,IHC,IF
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | IL18BP Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn’s disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-194 of human IL18BP (NP_001138529.1). |
Gene ID: | 10068 |
Swiss prot: | O95998 |
Molecular weight: | 12kDa/17kDa/21kDa |
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