Western blot analysis of extracts of various cell lines, using PRKCB antibody (A5845) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
PRKCB Rabbit pAb
Catalog No:AB-A5845
Manufacturer:ABclonal
Synonyms:PRKCB;PKC-beta;PKCB;PRKCB1;PRKCB2
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | PRKCB Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-340 of human PRKCB (NP_002729.2). |
Gene ID: | 5579 |
Swiss prot: | P05771 |
Molecular weight: | 76kDa/77kDa |
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