Western blot analysis of extracts of various cell lines, using ING3 antibody (A5832) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
ING3 Rabbit pAb
Catalog No:AB-A5832
Manufacturer:ABclonal
Synonyms:ING3;Eaf4;ING2;MEAF4;p47ING3
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ING3 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human ING3 (NP_938008.1). |
Gene ID: | 54556 |
Swiss prot: | Q9NXR8 |
Molecular weight: | 11kDa/46kDa |
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