Western blot analysis of extracts of various cell lines, using MECOM antibody (A5674) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
MECOM Rabbit pAb
Catalog No:AB-A5674
Manufacturer:ABclonal
Synonyms:MECOM;AML1-EVI-1;EVI1;KMT8E;MDS1;MDS1-EVI1;PRDM3;RUSAT2
Applications:WB
Reactivity:Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MECOM Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human MECOM (NP_004982.2). |
Gene ID: | 2122 |
Swiss prot: | Q03112/Q13465 |
Molecular weight: | 18kDa/117kDa/118kDa/125kDa/139kDa |
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