Western blot analysis of extracts of mouse testis, using PIAS2 antibody (A5654) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
PIAS2 Rabbit pAb
Catalog No:AB-A5654
Manufacturer:ABclonal
Synonyms:PIAS2;ARIP3;DIP;MIZ;MIZ1;PIASX;PIASX-ALPHA;PIASX-BETA;SIZ2;ZMIZ4
Applications:WB,IHC
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | PIAS2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 483-572 of human PIAS2 (NP_775298.1). |
Gene ID: | 9063 |
Swiss prot: | O75928 |
Molecular weight: | 45kDa/63kDa/68kDa |
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