Western blot analysis of extracts of THP-1 cells, using LAT Rabbit pAb (A5650) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
LAT Rabbit pAb
Catalog No:AB-A5650
Manufacturer:ABclonal
Synonyms:LAT;LAT1;pp36;IMD52
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | LAT Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-233 of human LAT (NP_001014987.1). |
Gene ID: | 27040 |
Swiss prot: | O43561 |
Molecular weight: | 24kDa/27kDa/28kDa |
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