Western blot analysis of extracts of various cell lines, using FMRP antibody (A5645) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 50s.
FMRP Rabbit pAb
Catalog No:AB-A5645
Manufacturer:ABclonal
Synonyms:FMRP;FRAXA;POF;POF1;FMR1;POFX
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | FMRP Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5′ UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human FMRP (NP_001172011.1). |
Gene ID: | 2332 |
Swiss prot: | Q06787 |
Molecular weight: | 58kDa/61kDa/66kDa/68kDa/69kDa/70kDa/71kDa |
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