XPD/ERCC2 Rabbit pAb
Catalog No:AB-A5640
Manufacturer:ABclonal
Synonyms:ERCC2;COFS2;EM9;TFIIH;TTD;TTD1;XPD
Applications:WB,IF
Reactivity:Human,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | XPD/ERCC2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human XPD/XPD/ERCC2 (NP_001124339.1). |
Gene ID: | 2068 |
Swiss prot: | P18074 |
Molecular weight: | 46kDa/86kDa |
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