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Western blot analysis of extracts of various cell lines, using CD105 antibody (A5639) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 30s.
CD105 Rabbit pAb
Catalog No：AB-A5639
Manufacturer：ABclonal
Synonyms：END;HHT1;ORW1;CD105;ENG;endoglin
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | CD105 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-306 of human CD105 (NP_001108225.1). |
| Gene ID: | 2022 |
| Swiss prot: | P17813 |
| Molecular weight: | 67kDa/70kDa |
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