Western blot analysis of extracts of various cell lines, using DCLRE1C antibody (A5615) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
DCLRE1C Rabbit pAb
Catalog No:AB-A5615
Manufacturer:ABclonal
Synonyms:DCLRE1C;A-SCID;DCLREC1C;RS-SCID;SCIDA;SNM1C
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €325,00
Product Name: | DCLRE1C Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5′-3′ exonuclease activity; it also exhibits endonuclease activity on 5′ and 3′ overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DCLRE1C (NP_001029027.1). |
Gene ID: | 64421 |
Swiss prot: | Q96SD1 |
Molecular weight: | 49kDa/64kDa/65kDa/78kDa |
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