.jpg)
Western blot analysis of extracts of various cell lines, using AKT1 antibody (A5523) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
AKT1 Rabbit pAb
Catalog No：AB-A5523
Manufacturer：ABclonal
Synonyms：AKT;CWS6;PKB;PKB-ALPHA;PRKBA;RAC;RAC-ALPHA;AKT1
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | AKT1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human AKT1 (NP_005154.2). |
| Gene ID: | 207 |
| Swiss prot: | P31749 |
| Molecular weight: | 48kDa/55kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No：AB-A0130
Manufacturer：ABclonal
Synonyms：LRP5;BMND1;EVR1;EVR4;HBM;LR3;LRP-5;LRP7;OPPG;OPS;OPTA1;VBCH2
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0076
Manufacturer：ABclonal
Synonyms：BDPLT16;BDPLT2;CD61;GP3A;GPIIIa;GT;Integrin beta 3;ITGB3
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0059
Manufacturer：ABclonal
Synonyms：BSCL3;CGL3;LCCNS;MSTP085;PPH3;VIP21;CAV1
Applications：IF
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0062
Manufacturer：ABclonal
Synonyms：CYP1A2;CP12;P3-450;P450(PA);CYPIA2
Applications：WB
Reactivity：Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0047
Manufacturer：ABclonal
Synonyms：DHQU;DIA4;DTD;NMOR1;NMORI;QR1;NQO1
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0008
Manufacturer：ABclonal
Synonyms：10q23del;BZS;CWS1;DEC;GLM2;MHAM;MMAC1;PTEN1;TEP1;PTEN;PTENbeta
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00