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Western blot analysis of extracts of various cell lines, using Thioredoxin reductase 2 (Thioredoxin reductase 2 (TXNRD2 ) ) antibody (A5490) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded human liver cancer using Thioredoxin reductase 2 (Thioredoxin reductase 2 (TXNRD2 ) ) antibody (A5490) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human liver damage using Thioredoxin reductase 2 (Thioredoxin reductase 2 (TXNRD2 ) ) antibody (A5490) at dilution of 1:100 (40x lens).
Thioredoxin reductase 2 (TXNRD2 ) Rabbit pAb
Catalog No：AB-A5490
Manufacturer：ABclonal
Synonyms：TXNRD2;SELZ;TR;TR-BETA;TR3;TRXR2
Applications：WB,IHC
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | Thioredoxin reductase 2 (TXNRD2 ) Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes a mitochondrial form important for scavenging reactive oxygen species in mitochondria. It functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3′ UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms, including a few localized in the cytosol and some lacking the C-terminal Sec residue, have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-310 of human Thioredoxin reductase 2 (Thioredoxin reductase 2 (TXNRD2 ) ) (NP_006431.2). |
| Gene ID: | 10587 |
| Swiss prot: | Q9NNW7 |
| Molecular weight: | 30kDa/46kDa/53kDa/56kDa |
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