Western blot analysis of extracts of various cell lines, using LGI1 antibody (A5408) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
LGI1 Rabbit pAb
Catalog No:AB-A5408
Manufacturer:ABclonal
Synonyms:LGI1;ADLTE;ADPAEF;ADPEAF;EPITEMPIN;EPT;ETL1;IB1099
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | LGI1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 301-557 of human LGI1 (NP_005088.1). |
Gene ID: | 9211 |
Swiss prot: | O95970 |
Molecular weight: | 33kDa/58kDa/63kDa |
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