Western blot analysis of extracts of various cell lines, using RCAN1 antibody (A5326) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
RCAN1 Rabbit pAb
Catalog No:AB-A5326
Manufacturer:ABclonal
Synonyms:RCAN1;ADAPT78;CSP1;DSC1;DSCR1;MCIP1;RCN1
Applications:WB,IHC,IF
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | RCAN1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-245 of human RCAN1 (NP_004405.3). |
Gene ID: | 1827 |
Swiss prot: | P53805 |
Molecular weight: | 13kDa/19kDa/22kDa/28kDa |
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