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Western blot analysis of extracts of various cell lines, using SESN3 antibody (A5164) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
SESN3 Rabbit pAb
Catalog No：AB-A5164
Manufacturer：ABclonal
Synonyms：SESN3;SEST3;sestrin-3
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | SESN3 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human SESN3 (NP_653266.2). |
| Gene ID: | 143686 |
| Swiss prot: | P58005 |
| Molecular weight: | 36kDa/41kDa/57kDa |
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