Western blot analysis of extracts of various cell lines, using MBNL1 Rabbit mAb (A5149) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
MBNL1 Rabbit mAb
Catalog No:AB-A5149
Manufacturer:ABclonal
Synonyms:EXP, MBNL
Applications:WB,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | MBNL1 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015] |
Immunogen: | A synthesized peptide derived from human MBNL1 |
Gene ID: | 4154 |
Swiss prot: | Q9NR56 |
Molecular weight: | 40kDa |
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