Western blot analysis of extracts of HT-29 cells, using TIMP1 Rabbit mAb (A4959) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
TIMP1 Rabbit mAb
Catalog No:AB-A4959
Manufacturer:ABclonal
Synonyms:CLGI, EPA, EPO, HCI, TIMP, TIMP-1
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | TIMP1 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008] |
Immunogen: | A synthesized peptide derived from human TIMP1 |
Gene ID: | 7076 |
Swiss prot: | P01033 |
Molecular weight: | 26kDa |
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