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Western blot analysis of extracts of various cell lines, using Caspase-2 pAb (A4888) at 1:1000 dilution.Jurkat cells were treated by Staurosporine (1uM) for 3 hours.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
Caspase-2 Rabbit mAb
Catalog No：AB-A4888
Manufacturer：ABclonal
Synonyms：CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57
Applications：WB
Reactivity：Human,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | Caspase-2 Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |
| Immunogen: | A synthesized peptide derived from human Caspase-2 |
| Gene ID: | 835 |
| Swiss prot: | P42575 |
| Molecular weight: | 12kDa/30kDa/48kDa |
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