Western blot analysis of extracts of BxPC-3 cells, using JunB Rabbit mAb (A4848) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
JunB Rabbit mAb
Catalog No:AB-A4848
Manufacturer:ABclonal
Synonyms:AP-1
Applications:WB,IHC
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | JunB Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | JunB is one of the components of the Activator Protein-1 (AP-1) transcription complex that have been implicated in the control ofthe G0/G1 transtion in fibroblasts. AP-1 is a collection of dimers formed by members of the Jun-, Fos-, ATF- and Maf multigene families that bind to specific DNA regulatory elements called AP-1/12-O-tetradecanoylphorbol-13-acetate-responsive elements (TREs) and cAMP-responsive elements (CREs). JunB binds to the DNA sequence 5′-TGA[CG]TCA-3′, and involves in the regulation of gene activity following the primary growth factor response. It also acts either as a tumor suppressor or as an oncogene depending on the cell and physiopathological context |
Immunogen: | A synthesized peptide derived from human JunB |
Gene ID: | 3726 |
Swiss prot: | P17275 |
Molecular weight: | 43kDa |
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