Western blot analysis of extracts of various cell lines, using SMC1 Rabbit mAb (A4693) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3s.
Western blot analysis of extracts of various cell lines, using SMC1 Rabbit mAb (A4693) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
SMC1 Rabbit mAb
Catalog No:AB-A4693
Manufacturer:ABclonal
Synonyms:CDLS2, DXS423E, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | SMC1 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] |
Immunogen: | A synthesized peptide derived from human SMC1 |
Gene ID: | 8243 |
Swiss prot: | Q14683 |
Molecular weight: | 143kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No:AB-A0109
Manufacturer:ABclonal
Synonyms:D3F15S2, DNF15S2, HGFL, MSP, NF15S2
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Catalog No:AB-A0099
Manufacturer:ABclonal
Synonyms:EEF2;EEF-2;EF-2;EF2;SCA26
Applications:WB,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0064
Manufacturer:ABclonal
Synonyms:MSH2;COCA1;FCC1;HNPCC;HNPCC1;LCFS2
Applications:WB,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€245,00 – €370,00
Catalog No:AB-A0047
Manufacturer:ABclonal
Synonyms:DHQU;DIA4;DTD;NMOR1;NMORI;QR1;NQO1
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0036
Manufacturer:ABclonal
Synonyms:HEL-S-94n, HOP, IEF-SSP-3521, P60, STI1, STI1L
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Catalog No:AB-A0010
Manufacturer:ABclonal
Synonyms:ADPRT;ADPRT 1;ADPRT1;ARTD1;PARP;PARP-1;PPOL;pADPRT-1;PARP1;Cleaved PARP;PARP1
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €605,00