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Western blot analysis of extracts of B-cell cells, using TBX21 antibody (A4682) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
TBX21 Rabbit pAb
Catalog No：AB-A4682
Manufacturer：ABclonal
Synonyms：TBX21;T-PET;T-bet;TBET;TBLYM;T-box 21
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | TBX21 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 326-535 of human TBX21 (NP_037483.1). |
| Gene ID: | 30009 |
| Swiss prot: | Q9UL17 |
| Molecular weight: | 58kDa |
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