Western blot analysis of extracts of K-562 cells, using SIGLEC5 antibody (A4250) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
SIGLEC5 Rabbit pAb
Catalog No:AB-A4250
Manufacturer:ABclonal
Synonyms:SIGLEC5;CD170;CD33L2;OB-BP2;OBBP2;SIGLEC-5
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | SIGLEC5 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 452-551 of human SIGLEC5 (NP_003821.1). |
Gene ID: | 8778 |
Swiss prot: | O15389 |
Molecular weight: | 60kDa |
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