Western blot analysis of extracts of various cell lines, using MRE11 Rabbit mAb (A4222) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
MRE11 Rabbit mAb
Catalog No:AB-A4222
Manufacturer:ABclonal
Synonyms:ATLD, HNGS1, MRE11A, MRE11B
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | MRE11 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
Immunogen: | A synthesized peptide derived from human MRE11 |
Gene ID: | 4361 |
Swiss prot: | P49959 |
Molecular weight: | 81kDa |
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