Western blot analysis of extracts of various cell lines, using EAAT2/SLC1A2 Rabbit mAb (A3679) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
EAAT2/SLC1A2 Rabbit mAb
Catalog No:AB-A3679
Manufacturer:ABclonal
Synonyms:EAAT2, EIEE41, GLT-1, HBGT
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | EAAT2/SLC1A2 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010] |
Immunogen: | A synthesized peptide derived from human EAAT2/SLC1A2 |
Gene ID: | 6506 |
Swiss prot: | P43004 |
Molecular weight: | 62kDa |
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