Western blot analysis of extracts of HL-60 cells, using MXD1 antibody (A3613) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 90s.
MXD1 Rabbit pAb
Catalog No:AB-A3613
Manufacturer:ABclonal
Synonyms:MXD1;BHLHC58;MAD;MAD1
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MXD1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human MXD1 (NP_002348.1). |
Gene ID: | 4084 |
Swiss prot: | Q05195 |
Molecular weight: | 24kDa/25kDa |
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