Western blot analysis of extracts of various cell lines, using GFM2 antibody (A10158) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
GFM2 Rabbit pAb
Catalog No:AB-A10158
Manufacturer:ABclonal
Synonyms:GFM2;EF-G2mt;EFG2;MRRF2;MST027;MSTP027;RRF2;RRF2mt;hEFG2;mEF-G 2;mEF-G2
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | GFM2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA . Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-779 of human GFM2 (NP_115756.2). |
Gene ID: | 84340 |
Swiss prot: | Q969S9 |
Molecular weight: | 57kDa/67kDa/81kDa/86kDa |
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