Western blot analysis of extracts of various cell lines, using Integrin alpha 6 (ITGA6/CD49f) antibody (A3236) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
Integrin alpha 6 (ITGA6/CD49f) Rabbit pAb
Catalog No:AB-A3236
Manufacturer:ABclonal
Synonyms:CD49f;ITGA6B;VLA-6;Integrin alpha 6;ITGA6
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | Integrin alpha 6 (ITGA6/CD49f) Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 870-1010 of human Integrin alpha 6 (ITGA6/CD49f) (NP_001073286.1). |
Gene ID: | 3655 |
Swiss prot: | P23229 |
Molecular weight: | 106kDa/119kDa/121kDa/122kDa/124kDa/126kDa |
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