TTR Rabbit pAb
Catalog No:AB-A3186
Manufacturer:ABclonal
Synonyms:TTR;CTS;CTS1;HEL111;HsT2651;PALB;TBPA
Applications:IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | TTR Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. |
Immunogen: | Recombinant protein of human TTR |
Gene ID: | 7276 |
Swiss prot: | P02766 |
Molecular weight: | 15kDa |
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