Western blot analysis of extracts of various cell lines, using MMP17 Rabbit pAb (A3030) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
MMP17 Rabbit pAb
Catalog No:AB-A3030
Manufacturer:ABclonal
Synonyms:MMP17;MMP-17;MT4-MMP;MT4MMP;MTMMP4
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MMP17 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein is unique among the membrane-type matrix metalloproteinases in that it is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor. Elevated expression of the encoded protein has been observed in osteoarthritis and multiple human cancers. |
Immunogen: | A synthetic peptide of human MMP17 |
Gene ID: | 4326 |
Swiss prot: | Q9ULZ9 |
Molecular weight: | 57kDa/66kDa |
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