Western blot analysis of extracts of THP-1 cells, using IL15RA antibody (A2983) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 180s.
IL15RA Rabbit pAb
Catalog No:AB-A2983
Manufacturer:ABclonal
Synonyms:IL15RA;CD215
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€245,00 – €370,00
Product Name: | IL15RA Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-205 of human IL15RA (NP_002180.1). |
Gene ID: | 3601 |
Swiss prot: | Q13261 |
Molecular weight: | 15-28kDa |
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