Western blot analysis of extracts of various cell lines, using GNAS antibody (A2732) at 1:400 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
GNAS Rabbit pAb
Catalog No:AB-A2732
Manufacturer:ABclonal
Synonyms:GNAS;AHO;C20orf45;GNAS1;GPSA;GSA;GSP;NESP;POH;SCG6;SgVI
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | GNAS Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5′ exons. Some transcripts contain a differentially methylated region (DMR) at their 5′ exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein – Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors. |
Immunogen: | Recombinant protein of human GNAS |
Gene ID: | 2778 |
Swiss prot: | O95467/P63092/P84996/Q5JWF2 |
Molecular weight: | 28kDa/44kDa/45kDa/77kDa/109kDa/111kDa |
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Catalog No:AB-A0098
Manufacturer:ABclonal
Synonyms:ATP2B;DAR;DD;SERCA2;ATP2A2/SERCA2;ATP2A2
Applications:WB,IHC
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0082
Manufacturer:ABclonal
Synonyms:FGFR1;BFGFR;CD331;CEK;ECCL;FGFBR;FGFR-1;FLG;FLT-2;FLT2;HBGFR;HH2;HRTFDS;KAL2;N-SAM;OGD;bFGF-R-1
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0064
Manufacturer:ABclonal
Synonyms:MSH2;COCA1;FCC1;HNPCC;HNPCC1;LCFS2
Applications:WB,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€245,00 – €370,00
Catalog No:AB-A0054
Manufacturer:ABclonal
Synonyms:AGM7;GRB1;IMD36;p85;p85-ALPHA;PI3 Kinase p85 alpha;PIK3R1
Applications:WB,IHC
Reactivity:Human,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0040
Manufacturer:ABclonal
Synonyms:MET;AUTS9;DFNB97;HGFR;RCCP2;c-Met
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0008
Manufacturer:ABclonal
Synonyms:10q23del;BZS;CWS1;DEC;GLM2;MHAM;MMAC1;PTEN1;TEP1;PTEN;PTENbeta
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00