Western blot analysis of extracts of various cell lines, using TNXB antibody (A2535) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
TNXB Rabbit pAb
Catalog No:AB-A2535
Manufacturer:ABclonal
Synonyms:TNXB;EDS3;HXBL;TENX;TN-X;TNX;TNXB1;TNXB2;TNXBS;VUR8;XB;XBS
Applications:WB
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | TNXB Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5′ and 3′ ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 444-673 of human TNXB (NP_115859.2). |
Gene ID: | 7148 |
Swiss prot: | P22105 |
Molecular weight: | 74kDa/458kDa |
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