Western blot analysis of extracts of various cell lines, using HNMT antibody (A2520) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
HNMT Rabbit pAb
Catalog No:AB-A2520
Manufacturer:ABclonal
Synonyms:HNMT;HMT;HNMT-S1;HNMT-S2;MRT51
Applications:WB,IF,IP
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | HNMT Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human HNMT (NP_008826.1). |
Gene ID: | 3176 |
Swiss prot: | P50135 |
Molecular weight: | 6kDa/14kDa/33kDa |
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