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Western blot analysis of extracts of various cell lines, using HSPB8/HSP22 antibody (A2514) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
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Immunohistochemistry of paraffin-embedded rat heart using HSPB8/HSP22 Rabbit pAb (A2514) at dilution of 1:100 (40x lens).
HSPB8/HSP22 Rabbit pAb
Catalog No：AB-A2514
Manufacturer：ABclonal
Synonyms：HSPB8;CMT2L;DHMN2;E2IG1;H11;HMN2;HMN2A;HSP22
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | HSPB8/HSP22 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-196 of human HSPB8/HSP22 (NP_055180.1). |
| Gene ID: | 26353 |
| Swiss prot: | Q9UJY1 |
| Molecular weight: | 21kDa |
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