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Western blot analysis of extracts of various cell lines, using FLNB antibody (A2481) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Basic Kit (RM00020)._Exposure time: 10s.
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Immunohistochemistry of paraffin-embedded rat heart using FLNB antibody (A2481) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human liver damage using FLNB antibody (A2481) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human prostate using FLNB antibody (A2481) at dilution of 1:100 (40x lens).
FLNB Rabbit pAb
Catalog No：AB-A2481
Manufacturer：ABclonal
Synonyms：FLNB;ABP-278;ABP-280;AOI;FH1;FLN-B;FLN1L;LRS1;SCT;TABP;TAP;filamin-B
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | FLNB Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1686-1785 of human FLNB (NP_001157789.1). |
| Gene ID: | 2317 |
| Swiss prot: | O75369 |
| Molecular weight: | 230-281kDa |
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