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Western blot analysis of extracts of various cell lines, using UHRF2 antibody (A2344) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
Uhrf2 Rabbit pAb
Catalog No：AB-A2344
Manufacturer：ABclonal
Synonyms：UHRF2;NIRF;RNF107;TDRD23;URF2;Uhrf2
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | Uhrf2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 76-359 of mouse Uhrf2 (NP_659122.2). |
| Gene ID: | 109113 |
| Swiss prot: | Q7TMI3 |
| Molecular weight: | 56kDa/89kDa |
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