CYP1A1 Rabbit pAb
Catalog No:AB-A2159
Manufacturer:ABclonal
Synonyms:CYP1A1;AHH;AHRR;CP11;CYP1;CYPIA1;P1-450;P450-C;P450DX
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CYP1A1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme’s endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-460 of human CYP1A1 (NP_000490.1). |
Gene ID: | 1543 |
Swiss prot: | P04798 |
Molecular weight: | 18kDa/20kDa/58kDa |
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