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Western blot analysis of extracts of HeLa cells, using Zyxinin antibody (A2135).|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.
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Immunohistochemistry of paraffin-embedded mouse spleen using Zyxinin antibody (A2135) at dilution of 1:100 (40x lens).
Zyxin Rabbit pAb
Catalog No：AB-A2135
Manufacturer：ABclonal
Synonyms：ZYX;ESP-2;HED-2;zyxin
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | Zyxin Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human Zyxinin (NP_001010972.1). |
| Gene ID: | 7791 |
| Swiss prot: | Q15942 |
| Molecular weight: | 45kDa/61kDa |
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