Western blot analysis of extracts of various cell lines, using TYK2 antibody (A2128) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
TYK2 Rabbit pAb
Catalog No:AB-A2128
Manufacturer:ABclonal
Synonyms:TYK2;IMD35;JTK1
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | TYK2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) – a primary immunodeficiency characterized by elevated serum immunoglobulin E. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 750-850 of human TYK2 (NP_003322.3). |
Gene ID: | 7297 |
Swiss prot: | P29597 |
Molecular weight: | 133kDa |
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