Western blot analysis of extracts of various cell lines, using CDKN1C/p57 Kip2 antibody (A2060) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
CDKN1C/p57 Kip2 Rabbit pAb
Catalog No:AB-A2060
Manufacturer:ABclonal
Synonyms:CDKN1C;BWCR;BWS;KIP2;WBS;p57;p57Kip2
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CDKN1C/p57 Kip2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDKN1C/p57 Kip2 (NP_000067.1). |
Gene ID: | 1028 |
Swiss prot: | P49918 |
Molecular weight: | 31kDa/32kDa |
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