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Western blot analysis of extracts of rat skeletal muscle, using CHRNA2 antibody (A10056) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
CHRNA2 Rabbit pAb
Catalog No：AB-A10056
Manufacturer：ABclonal
Synonyms：CHRNA2
Applications：WB
Reactivity：Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | CHRNA2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-264 of human CHRNA2 (NP_000733.2). |
| Gene ID: | 1135 |
| Swiss prot: | Q15822 |
| Molecular weight: | 58kDa/59kDa |
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