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Immunofluorescence analysis of NIH/3T3 cells using Syntrophin alpha 1 Rabbit pAb (A20460) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.
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Immunofluorescence analysis of PC-12 cells using Syntrophin alpha 1 Rabbit pAb (A20460) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.
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Western blot analysis of extracts of various cell lines, using Syntrophin alpha 1 antibody (A20460) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
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Western blot analysis of extracts of various cell lines, using Syntrophin alpha 1 antibody (A20460) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
Syntrophin alpha 1 Rabbit pAb
Catalog No：AB-A20460
Manufacturer：ABclonal
Synonyms：LQT12, SNT1, TACIP1, dJ1187J4.5
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€125,00 – €370,00
| Product Name: | Syntrophin alpha 1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) – an inherited disorder associated with sudden cardiac death from arrhythmia – and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013] |
| Immunogen: | Recombinant protein of human Syntrophin alpha 1. |
| Gene ID: | 6640 |
| Swiss prot: | Q13424 |
| Molecular weight: | 54kDa |
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